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大鼠第三脑室中胶质纤维酸性蛋白样免疫反应性室管膜成分。不同发育阶段的研究。

Glial fibrillary acidic protein-like immunoreactive ependymal elements in the third ventricle of the rat. A study at different stages of development.

作者信息

Juanes J A, Riesco J M, Sánchez F, Carretero J, Blanco E, Vázquez R

机构信息

Departamento de Anatomía e Histología Humanas, Facultad de Medicina, Universidad de Salamanca, Spain.

出版信息

Acta Anat (Basel). 1992;145(4):364-9. doi: 10.1159/000147390.

DOI:10.1159/000147390
PMID:10457777
Abstract

Using the peroxidase-antiperoxidase method a study was made of the cells immunoreactive to glial fibrillary acidic protein (GFAP) anti-serum in the ependyma of the third ventricle of the rat at different stages of growth. Most of the ependymal cells of the third ventricle were seen to be unreactive to this protein; however, it was sometimes possible to observe some GFAP-immunoreactive ependymocytes and occasionally other immunoreactive cellular types, such as tanycytes and supraependymal cells. Despite this, the most frequent localization of the elements immunoreactive to the protein adopted the shape of an immunoreactive subependymal band situated parallel to the ventricular wall. As the weights of the animals increased an increase in the elements immunoreactive to this protein could be observed in all the zones considered, there being no differences between the male and female animals.

摘要

采用过氧化物酶 - 抗过氧化物酶法,对不同生长阶段大鼠第三脑室室管膜中对胶质纤维酸性蛋白(GFAP)抗血清呈免疫反应的细胞进行了研究。可见第三脑室的大多数室管膜细胞对该蛋白无反应;然而,有时可以观察到一些GFAP免疫反应性室管膜细胞,偶尔还有其他免疫反应性细胞类型,如伸展细胞和室管膜上细胞。尽管如此,对该蛋白呈免疫反应的成分最常见的定位呈平行于室壁的免疫反应性室管膜下带的形状。随着动物体重增加,在所考虑的所有区域中均可观察到对该蛋白呈免疫反应的成分增加,雄性和雌性动物之间无差异。

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