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慢性肾衰竭患者的角膜内皮变化

Corneal endothelial changes in patients with chronic renal failure.

作者信息

Ohguro N, Matsuda M, Fukuda M

机构信息

Department of Ophthalmology, Osaka University Medical School, Suita, Japan.

出版信息

Am J Ophthalmol. 1999 Aug;128(2):234-6. doi: 10.1016/s0002-9394(99)00086-0.

Abstract

PURPOSE

To evaluate the morphologic changes of the corneal endothelium in patients with chronic renal failure.

METHODS

Twenty corneas of 20 patients with chronic renal failure undergoing hemodialysis were examined by wide-field specular microscopy. Twenty normal corneas from 20 healthy age-matched subjects were enrolled as control corneas.

RESULTS

Despite normal endothelial cell density, the corneal endothelium of patients with chronic renal failure showed marked polymegethism and pleomorphism.

CONCLUSION

Polymegethism and pleomorphism of the corneal endothelium are found in patients with chronic renal failure.

摘要

目的

评估慢性肾衰竭患者角膜内皮的形态学变化。

方法

采用广域角膜内皮显微镜检查20例接受血液透析的慢性肾衰竭患者的20只角膜。选取20例年龄匹配的健康受试者的20只正常角膜作为对照角膜。

结果

尽管内皮细胞密度正常,但慢性肾衰竭患者的角膜内皮出现明显的大小不均一性和形态多样。

结论

慢性肾衰竭患者存在角膜内皮大小不均一性和形态多样。

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