Han S W, Lee T, Kim J H, Choi S K, Cho N H, Han J Y
Department of Urology, Yonsei University College of Medicine, Seoul, Korea.
J Urol. 1999 Sep;162(3 Pt 1):878-80. doi: 10.1097/00005392-199909010-00082.
We compared testicular biopsies from retractile and cryptorchid testes to determine the histological effect of testicular retraction and the necessity of treatment for retractile testes.
A total of 61 testicular biopsies were performed during orchiopexy in 36 boys 1.3 to 9.8 years old (mean age 5.4) with retractile testes (unilateral in 11, bilateral in 50) and 115 testicular biopsies were done in 83 patients with cryptorchidism (unilateral in 51, bilateral in 64) 0.5 to 14.9 years old (mean age 3.7). Parameters for germ and Sertoli cells were determined in each group.
Mean average spermatogonial number (S/T value) and Sertoli cell index were statistically different between retractile and cryptorchid testes with values of 2.96+/-1.33 versus 0.61+/-0.87 and 26.81+/-6.75 versus 23.04+/-5.85, respectively. Average tubular degeneration phase V to VII ratio was 0.23+/-0.18 for retractile testes and 0.22+/-0.17 for cryptorchid testes which was not statistically different.
Similar tubular degeneration phase V to VII values between retractile and cryptorchid testes indicate histological change in retractile testes and suggest the need for hormonal or surgical therapy for those patients with retractile testes lacking spontaneous descent.
我们比较了回缩性睾丸和隐睾的睾丸活检结果，以确定睾丸回缩的组织学影响以及回缩性睾丸治疗的必要性。
对36名年龄在1.3至9.8岁（平均年龄5.4岁）的回缩性睾丸男孩（单侧11例，双侧50例）进行睾丸固定术时共进行了61次睾丸活检，对83例年龄在0.5至14.9岁（平均年龄3.7岁）的隐睾患者（单侧51例，双侧64例）进行了115次睾丸活检。测定了每组中生殖细胞和支持细胞的参数。
回缩性睾丸和隐睾之间的平均精原细胞数（S/T值）和支持细胞指数在统计学上有差异，分别为2.96±1.33和0.61±0.87，以及26.81±6.75和23.04±5.85。回缩性睾丸的平均V至VII期小管退变率为0.23±0.18，隐睾为0.22±0.17，两者无统计学差异。
回缩性睾丸和隐睾之间相似的V至VII期小管退变值表明回缩性睾丸存在组织学变化，并提示对于那些睾丸未自发下降的回缩性睾丸患者需要进行激素或手术治疗。
