Roenigk H H
Arizona Advanced Dermatology, 500 W Thomas Road, Suite 360, Phoenix, AZ 85013, USA.
J Am Acad Dermatol. 1999 Sep;41(3 Pt 2):S18-21. doi: 10.1016/s0190-9622(99)70361-0.
Systemic therapies used in psoriasis such as methotrexate, PUVA, cyclosporine, and acitretin often have side effects that limit their usefulness. Combination therapy, an effective strategy for treating psoriasis, allows use of lower doses of medications to achieve superior therapeutic results with fewer side effects. Acitretin is one of the most popular drugs used in combination with other systemic therapies for psoriasis. Details of the regimens used and results obtained from combining acitretin with PUVA, cyclosporine, and methotrexate are discussed.
用于治疗银屑病的全身疗法，如甲氨蝶呤、补骨脂素紫外线A光化学疗法（PUVA）、环孢素和阿维A，常常存在副作用，限制了它们的效用。联合疗法是治疗银屑病的一种有效策略，它允许使用较低剂量的药物，以在副作用较少的情况下取得更好的治疗效果。阿维A是与其他银屑病全身疗法联合使用的最常用药物之一。本文讨论了阿维A与PUVA、环孢素和甲氨蝶呤联合使用的治疗方案细节及取得的结果。
