Matioli G T
USC Medical School, Los Angeles, CA 90033, USA.
Med Hypotheses. 1999 Jun;52(6):521-3. doi: 10.1054/mehy.1997.0668.
The paper studies mammalian chromatids conformed as donut-like rings. Albeit enacting many topologic and dynamic aspects of straight chromatids (e.g. replication, eversion, antipodal segregation at anaphase, etc.), rings differ in certain properties regarding in particular disposal of soliton-like, kinked frustrations of their chirality during recurrent sister chromatid exchanges (SCEs).
该论文研究了呈甜甜圈状环形态的哺乳动物染色单体。尽管环状染色单体展现出了直染色单体的许多拓扑和动态特征(如复制、翻转、后期的反向分离等),但在反复的姐妹染色单体交换(SCEs)过程中,尤其是在处理类似孤子的、手性的扭结挫折方面,环状染色单体在某些特性上有所不同。