西索米星和其他四种氨基糖苷类药物对甲氧西林敏感和耐药菌株的抗葡萄球菌活性。
Antistaphylococcal activity of sisomicin and four other aminoglycosides against strains sensitive and resistant to methicillin.
作者信息
Yourassowsky E, Schoutens E, Vanderlinden M P
出版信息
Infection. 1975;3(3):148-9. doi: 10.1007/BF01641337.
PMID:1046008
Abstract
Five aminoglycosides were tested for inhibitory activity on 91 strains of Staphylococcus aureus, 39 of which were methicillin-resistant. The antistaphylococcal activity of these antibiotics was independent of the methicillin-resistance. Their order of decreasing effectiveness was: gentamicin greater than tobramycin = sisomicin greater than amikacin greater than kanamycin. Resistant strains were only found for the latter.
摘要
对5种氨基糖苷类药物针对91株金黄色葡萄球菌进行了抑制活性测试，其中39株为耐甲氧西林金黄色葡萄球菌。这些抗生素的抗葡萄球菌活性与耐甲氧西林特性无关。它们有效性递减的顺序为：庆大霉素＞妥布霉素 = 西索米星＞阿米卡星＞卡那霉素。仅发现后一种药物存在耐药菌株。
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