Hoagland R J
Prim Care. 1975 Jun;2(2):295-307.
Infectious mononucleosis is a unique disease in its hematologic aspects; it is different from the frequently occurring acute microbial diseases in that it affects primarily the reticuloendothelial system; and it is interesting serologically because of the heterophil antibody reaction, as well as the multiplicity of antibodies which may be produced. The diagnosis should be suspected clinically before hematology is reported - by remembering the prototypes. In fact, a patient between 16 and 25 years old who complains of sore throat and fever is more likely to have infectious mononucleosis than another disease; and if - in addition - he is jaundiced, a diagnosis of infectious mononucleosis is almost certain. Finally, a negative result of treatment with corticosteroid has the diagnostic significance mentioned above. Positive effect of treatment has no diagnostic significance.
传染性单核细胞增多症在血液学方面是一种独特的疾病；它与常见的急性微生物疾病不同，主要影响网状内皮系统；从血清学角度来看很有趣，因为存在嗜异性抗体反应以及可能产生的多种抗体。在血液学报告出来之前，临床上就应通过记住典型症状怀疑诊断。实际上，一名16至25岁抱怨喉咙痛和发烧的患者比患其他疾病更有可能患有传染性单核细胞增多症；此外，如果他出现黄疸，几乎可以肯定诊断为传染性单核细胞增多症。最后，皮质类固醇治疗的阴性结果具有上述诊断意义。治疗的阳性效果没有诊断意义。
