Hatch W V, Flanagan J G, Williams-Lyn D E, Buys Y M, Farra T, Trope G E
Glaucoma Research Unit, Toronto Western Hospital, Ontario, Canada.
J Glaucoma. 1999 Aug;8(4):232-7.
To measure the interobserver agreement of Heidelberg Retina Tomograph (HRT; Heidelberg Engineering, Heidelberg, Germany) parameters as a result of different observers' contour line placement.
The optic nerve heads of 50 patients with glaucoma were imaged with the HRT. Five observers traced each disc margin with a contour line. Each observer was masked to the contour line tracings of the other observers, and there was no formal discussion as to where to place the contour line. The following stereometric parameters were calculated for each image for each observer: disc area, mean height of contour, cup shape, rim volume using the standard reference plane from software version 1.11, rim volume using a reference plane of 320 microns below the retinal plane, and volume above curved surface. Agreement between the five observers was tested for each parameter using intraclass correlation coefficients (ICCs).
Interobserver agreement between the five observers was substantial for both rim volumes (ICC = 0.73) and for disc area (ICC = 0.67). Agreement was almost perfect for mean height of contour (ICC = 0.94), cup shape (ICC = 0.92), and volume above curved surface (ICC = 0.83).
The interobserver agreement for the HRT parameters was substantial to almost perfect, indicating that the HRT results as defined by the five observers were interchangeable.
测量不同观察者放置轮廓线导致的海德堡视网膜断层扫描仪（HRT；德国海德堡海德堡工程公司）参数的观察者间一致性。
用HRT对50例青光眼患者的视神经乳头进行成像。五名观察者用轮廓线描绘每个视盘边缘。每位观察者对其他观察者的轮廓线描绘不知情，并且没有关于轮廓线放置位置的正式讨论。为每位观察者的每张图像计算以下立体测量参数：视盘面积、轮廓平均高度、杯状形态、使用软件版本1.11的标准参考平面的视盘边缘体积、使用视网膜平面下方320微米的参考平面的视盘边缘体积以及曲面上方的体积。使用组内相关系数（ICC）对五个观察者之间的每个参数的一致性进行检验。
五个观察者之间对于视盘边缘体积（ICC = 0.73）和视盘面积（ICC = 0.67）的观察者间一致性较高。对于轮廓平均高度（ICC = 0.94）、杯状形态（ICC = 0.92）和曲面上方体积（ICC = 0.83）的一致性几乎为完美。
HRT参数的观察者间一致性较高至几乎完美，表明五名观察者定义的HRT结果具有互换性。
