Nagler A, Morecki S, Slavin S
Bone Marrow Transplantation Department, Hadassah University Hospital, Jerusalem, Israel.
Mol Biotechnol. 1999 Apr;11(2):181-94. doi: 10.1007/BF02915811.
Soybean agglutin (SBA) is a plant lectin that has been used to fractionate bone marrow cells. It binds bone marrow mononuclear cells, including mature myeloid, erythroid, and lymphoid cells, but has very low binding affinity and no toxic effect to the human hematopoietic cells. In this article we describe the possibilities of enriching bone-marrow-derived CD34+ hematopoietic progenitor cells using SBA. As the method is simple and elegant. SBA is of vast importance to the field of clinical bone marrow transplantation.
大豆凝集素（SBA）是一种植物凝集素，已被用于分离骨髓细胞。它能结合骨髓单个核细胞，包括成熟的髓系、红系和淋巴系细胞，但对人类造血细胞的结合亲和力非常低且无毒性作用。在本文中，我们描述了使用SBA富集骨髓来源的CD34+造血祖细胞的可能性。由于该方法简单且巧妙，SBA在临床骨髓移植领域具有极其重要的意义。
