Lankester K J, Brown R S, Spittle M F
Meyerstein Institute of Oncology, Middlesex Hospital, London, UK.
Clin Oncol (R Coll Radiol). 1999;11(3):208-10. doi: 10.1053/clon.1999.9046.
Angiosarcoma of the head and neck is a rare malignant vascular tumour that predominantly affects elderly men and generally has a poor prognosis. Complete responses to treatment for larger tumours are uncommon. A patient with an extensive tumour that showed a complete response to combination therapy with liposomal daunorubicin and radiotherapy is presented. The rationale for using liposomal chemotherapy agents in the treatment of vascular tumours such as angiosarcoma is discussed.
头颈部血管肉瘤是一种罕见的恶性血管肿瘤,主要影响老年男性,预后通常较差。较大肿瘤对治疗的完全缓解并不常见。本文介绍了一名患有广泛肿瘤的患者,该患者对脂质体柔红霉素与放疗的联合治疗表现出完全缓解。文中讨论了使用脂质体化疗药物治疗血管肉瘤等血管肿瘤的理论依据。