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1994 - 1995年酒精给药方法:研究人员关于研究对象和给药程序所报告及未报告的内容

Alcohol administration methodology 1994-1995: what researchers do and do not report about subjects and dosing procedures.

作者信息

Breslin F C, Sobell S L

机构信息

Centre for Addiction and Mental Health, and University of Toronto, ON, Canada.

出版信息

Addict Behav. 1999 Jul-Aug;24(4):509-20. doi: 10.1016/s0306-4603(99)00002-7.

Abstract

This article reviews which parts of the alcohol administration methodology were reported in 90 alcohol studies on humans published from 1994 to 1995. although several subject characteristics such as gender were regularly reported, other variables that can influence pharmacokinetics and responses to alcohol were not consistently reported. It is suggested that guidelines for reporting human alcohol administration studies be created and that journal editors and funding agencies require submissions to meet minimum standards for describing the study methodology. Potential guidelines are presented.

摘要

本文回顾了1994年至1995年发表的90项关于人类酒精研究中所报告的酒精给药方法的哪些部分。尽管一些受试者特征(如性别)经常被报告,但其他可能影响酒精药代动力学和反应的变量并未得到一致报告。建议制定人类酒精给药研究报告指南,并且期刊编辑和资助机构要求提交的报告符合描述研究方法的最低标准。文中给出了可能的指南。

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