Vuddhakul V, Tharavichitkul P, Na-Ngam N, Jitsurong S, Kunthawa B, Noimay P, Noimay P, Binla A, Thamlikitkul V
Department of Microbiology, Faculty of Science, Prince of Songkla University, Songkla, Thailand.
Am J Trop Med Hyg. 1999 Mar;60(3):458-61. doi: 10.4269/ajtmh.1999.60.458.
The distribution of Burkholderia pseudomallei in soil collected from four regions of Thailand and the frequency of B. pseudomallei infections in patients attending government hospitals throughout Thailand in 1997 were surveyed. A total of 3,585 soil samples collected from 896 sites in four regions of Thailand were cultured for B. pseudomallei using selective enrichment broth and modified Ashdown's agar. The organism was recovered in 4.4%, 6.1%, 20.4%, and 5.9% of the soil samples collected from the northern, central, northeastern, and southern regions, respectively, of Thailand (P < 0.0001). Burkholderia pseudomallei was cultured from 50.1% of the sites in the northeastern region compared with 13.8%, 24.5%, and 18.4% in the northern, central, and southern regions, respectively (P < 0.0001). The infection rate in patients attending government hospitals in the northeastern region (137.9 per 100,000 inpatients) was significantly higher than those in the northern (18 per 100,000 inpatients), central (13.4 per 100,000 inpatients), and southern (14.4 per 100,000 inpatients) regions, respectively (P < 0.0001). It is suggested that melioidosis, which is endemic in Thailand, is associated with the presence of B. pseudomallei in soil.
对从泰国四个地区采集的土壤中伯克霍尔德菌属类鼻疽杆菌的分布情况以及1997年泰国各地政府医院患者中类鼻疽杆菌感染的频率进行了调查。使用选择性富集肉汤和改良的阿什当琼脂对从泰国四个地区896个地点采集的总共3585份土壤样本进行类鼻疽杆菌培养。从泰国北部、中部、东北部和南部地区采集的土壤样本中，分别有4.4%、6.1%、20.4%和5.9%检测到该菌（P<0.0001）。类鼻疽杆菌在东北地区50.1%的采样点培养得到，而在北部、中部和南部地区的比例分别为13.8%、24.5%和18.4%（P<0.0001）。东北地区政府医院患者的感染率（每10万住院患者中有137.9例）显著高于北部（每10万住院患者中有18例）、中部（每10万住院患者中有13.4例）和南部（每10万住院患者中有14.4例）地区（P<0.0001）。研究表明，在泰国呈地方流行的类鼻疽病与土壤中类鼻疽杆菌的存在有关。
