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表现为红色鼻斑块的皮肤类鼻疽:一例报告

Cutaneous Melioidosis Presenting as a Red Nasal Plaque: A Case Report.

作者信息

Huang Sarocha, Santanirand Pitak, Chairanaicharoen Suwichak, Rattananukrom Teerapong

机构信息

Division of Dermatology, Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.

Clinical Pathology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.

出版信息

Infect Drug Resist. 2025 Jul 30;18:3779-3783. doi: 10.2147/IDR.S524877. eCollection 2025.

Abstract

BACKGROUND

Melioidosis, caused by , is endemic to tropical regions. Cutaneous forms, often presenting as non-healing ulcers, are rare and may mimic other skin diseases. Recognizing risk factors is key to prompt diagnosis and treatment.

CASE PRESENTATION

We report the case of a 51-year-old female with a 2-month history of chronic erythematous plaques on her nose. Aerobic tissue culture confirmed the diagnosis of primary cutaneous melioidosis by identifying . There was no evidence of systemic involvement, and blood culture results were negative. The patient was successfully treated with oral sulfamethoxazole-trimethoprim monotherapy. After three months of treatment, the lesion resolved completely, leaving an atrophic scar. At the eight-month follow-up, there was no evidence of recurrence.

CONCLUSION

This case illustrates an atypical presentation of cutaneous melioidosis without systemic involvement, which was effectively treated with oral sulfamethoxazole-trimethoprim monotherapy. A comprehensive evaluation to exclude dissemination is critical for ensuring successful treatment outcomes.

摘要

背景

类鼻疽病由[病原体名称未给出]引起,在热带地区为地方病。皮肤型类鼻疽病常表现为不愈合的溃疡,较为罕见,且可能类似其他皮肤病。识别风险因素是及时诊断和治疗的关键。

病例报告

我们报告一例51岁女性病例,其鼻部有2个月慢性红斑性斑块病史。需氧组织培养通过鉴定[病原体名称未给出]确诊为原发性皮肤类鼻疽病。无全身受累证据,血培养结果为阴性。患者接受口服复方磺胺甲恶唑单一疗法成功治疗。治疗三个月后,皮损完全消退,留下萎缩性瘢痕。在八个月的随访中,无复发证据。

结论

本病例说明了无全身受累的皮肤型类鼻疽病的非典型表现,口服复方磺胺甲恶唑单一疗法有效治疗了该病。进行全面评估以排除播散对于确保治疗成功至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6858/12318512/ec02da31d7b1/IDR-18-3779-g0001.jpg

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