Nouri K, Romagosa R, Chartier T, Bowes L, Spencer J M
Department of Dermatology, University of Miami, Florida 33101, USA.
Dermatol Surg. 1999 May;25(5):368-70. doi: 10.1046/j.1524-4725.1999.07320.x.
Striae distensae, or stretch marks, are a very common cosmetic problem. The successful management of stretch marks has long been a source of frustration and curiosity for both the clinician and the researcher. Recent studies suggest lasers may have a role in their management. As yet, no study has reported on the effects of either of these lasers in the treatment of stretch marks on persons with skin types 4 to 6.
To assess the efficacy of short pulsed CO2 laser and pulsed dye laser for the treatment of stretch marks in skin types 4, 5, and 6.
Four patients were initially enrolled in the study. All were female with abdominal stretch marks, present for a range of 8 to 19 years. The patients had skin types ranging from 4 to 6. The test area consisted of a stretch mark long enough to be divided into three contiguous 2 cm sections, labeled A, B, and C. Section A served as the short pulsed CO2 test site, section B served as a control, while section C served as the 585 nm pulsed dye site. Patients were seen for evaluation after 1 week, then every 4 weeks for a total of 20 weeks. Patients were evaluated subjectively by the investigators, and the patients' own self-evaluation was reported as well.
Following the 585 nm pulse dye laser, at 20 week follow-up patients with type 4 skin showed no improvement, while type 6 skin showed hyperpigmentation. The short pulsed CO2 test site showed persistent erythema in type 4 skin and marked hyperpigmentation in type 6 skin.
For patients with types 4, 5, and 6 skin, laser treatment of striae should be avoided or used with great caution.
膨胀纹，即妊娠纹，是一个非常常见的美容问题。长期以来，成功治疗妊娠纹一直是临床医生和研究人员感到沮丧和好奇的根源。最近的研究表明激光可能在其治疗中发挥作用。然而，尚无研究报道这两种激光对4至6型皮肤人群妊娠纹的治疗效果。
评估短脉冲二氧化碳激光和脉冲染料激光治疗4、5和6型皮肤妊娠纹的疗效。
最初有4名患者参与该研究。所有患者均为女性，有腹部妊娠纹，存在时间为8至19年。患者的皮肤类型为4至6型。测试区域由一条足够长的妊娠纹组成，可分为三个连续的2厘米部分，标记为A、B和C。A部分作为短脉冲二氧化碳测试部位，B部分作为对照，而C部分作为585纳米脉冲染料测试部位。1周后对患者进行评估，然后每4周评估一次，共评估20周。研究人员对患者进行主观评估，并报告患者自己的自我评估结果。
在585纳米脉冲染料激光治疗后，在20周的随访中，4型皮肤的患者没有改善，而6型皮肤出现色素沉着。短脉冲二氧化碳测试部位在4型皮肤中出现持续红斑，在6型皮肤中出现明显色素沉着。
对于4、5和6型皮肤的患者，应避免或极其谨慎地使用激光治疗妊娠纹。
