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治疗亚洲人白色膨胀纹:微聚焦超声-可视化与羟基磷灰石钙联合使用的疗效与安全性

Treating Striae Distensae Albae in Asians: Efficacy and Safety of Combined MFU-V and CaHA.

作者信息

Lim Joyce Teng Ee

机构信息

Joyce Lim Skin and Laser Clinic, Singapore.

出版信息

Plast Reconstr Surg Glob Open. 2021 Feb 25;9(2):e3429. doi: 10.1097/GOX.0000000000003429. eCollection 2021 Feb.

DOI:10.1097/GOX.0000000000003429
PMID:33680674
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7929617/
Abstract

UNLABELLED

This study evaluated the efficacy and safety of a single treatment combining microfocused ultrasound with visualization (MFU-V) and subdermal diluted calcium hydroxylapatite with lidocaine (CaHA+) for Striae Distensae Albae (SDA).

METHODS

Ten prospectively enrolled women with abdominal, back or thigh SDA were treated with MFU-V at 3 focal depths (4.5, 3.0, and 1.5 mm), followed by 3-6 mL of diluted CaHA+ (1:1 ratio) in the same session. Outcomes were assessed at 1 month, 3 months, and 5 months postprocedure using a 5-point quartile grading scale, an SDA scoring scale, a 10-point visual analog score, and a global aesthetic improvement scale.

RESULTS

All patients exhibited improvement in SDA at 3 months, with further improvement at 6 months. Physicians' assessment with the quartile grading scale showed that 8 patients improved moderately, whereas 2 had good improvement at 6 months. The mean overall SDA score was 11.6 at baseline, 11.1 (not significant) at 1 month, 7.9 ( = 0.005) at 3 months, and 6.2 ( = 0.005) at 6 months. All patients had improved global aesthetic improvement scale at 3 and 6 months, with 4 patients being much improved, and 3 patients being very much improved at 6 months. At the end of the study, all patients were less bothered with their SDA compared with baseline with a mean reduction of 2.7 in visual analog score, and all patients were satisfied or very satisfied with the treatment. No adverse events occurred.

CONCLUSION

A single combination treatment of MFU-V and diluted CaHA+ improves SDA without side effects and may be considered for patients seeking to minimize SDA.

摘要

未标注

本研究评估了微聚焦超声联合可视化(MFU-V)与皮下注射稀释的利多卡因羟基磷灰石(CaHA+)单一治疗方法对白色膨胀纹(SDA)的疗效和安全性。

方法

10名前瞻性招募的腹部、背部或大腿部有SDA的女性患者,在3个聚焦深度(4.5、3.0和1.5毫米)接受MFU-V治疗,随后在同一次治疗中注射3 - 6毫升稀释的CaHA+(1:1比例)。在治疗后1个月、3个月和5个月,使用5分四分位数分级量表、SDA评分量表、10分视觉模拟评分量表和整体美学改善量表对结果进行评估。

结果

所有患者在3个月时SDA均有改善,6个月时进一步改善。医生用四分位数分级量表评估显示,8例患者有中度改善,而2例在6个月时有良好改善。SDA总评分基线时平均为11.6,1个月时为11.1(无显著差异),3个月时为7.9(P = 0.005),6个月时为6.2(P = 0.005)。所有患者在3个月和6个月时整体美学改善量表评分均有提高,6个月时4例患者改善明显,3例患者改善非常明显。在研究结束时,与基线相比,所有患者对SDA的困扰均减轻,视觉模拟评分平均降低2.7,所有患者对治疗满意或非常满意。未发生不良事件。

结论

MFU-V与稀释的CaHA+联合单一治疗可改善SDA且无副作用,对于寻求最小化SDA的患者可考虑使用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ad73/7929617/3850286e5641/gox-9-e3429-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ad73/7929617/b37a191c9626/gox-9-e3429-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ad73/7929617/e918423af6c2/gox-9-e3429-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ad73/7929617/6bd8ccc77d89/gox-9-e3429-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ad73/7929617/3850286e5641/gox-9-e3429-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ad73/7929617/b37a191c9626/gox-9-e3429-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ad73/7929617/e918423af6c2/gox-9-e3429-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ad73/7929617/6bd8ccc77d89/gox-9-e3429-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ad73/7929617/3850286e5641/gox-9-e3429-g004.jpg

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