Ghali F E, Reed A M, Groben P A, McCauliffe D P
Department of Dermatology, University of North Carolina at Chapel Hill, USA.
Pediatr Dermatol. 1999 Jul-Aug;16(4):270-2. doi: 10.1046/j.1525-1470.1999.00059.x.
Panniculitis is a rarely reported clinical finding in dermatomyositis. We present a 14-year-old African American boy with a 4-year history of dermatomyositis referred for evaluation of tender, indurated plaques and nodules on the trunk and proximal extremities. A biopsy specimen revealed epidermal and dermal changes consistent with dermatomyositis. Although calcification was absent, a striking lobular panniculitis was observed. A total of seven cases of clinical panniculitis in association with dermatomyositis have been published. As in our patient, it typically presents as indurated, tender plaques and nodules on the arms, thighs, and buttocks. Although in the vast majority of cases panniculitis found in association with dermatomyositis is subclinical and represents an incidental histopathologic finding, the case we present further emphasizes the need to recognize panniculitis as a rare, but clinically relevant pathologic feature seen in certain lesions of juvenile dermatomyositis.
脂膜炎是皮肌炎中一种鲜有报道的临床发现。我们报告一名14岁非裔美国男孩,有4年皮肌炎病史,因躯干及近端肢体出现压痛性硬结斑块和结节前来评估。活检标本显示表皮和真皮变化符合皮肌炎表现。虽无钙化,但观察到显著的小叶性脂膜炎。共有7例与皮肌炎相关的临床脂膜炎病例已发表。与我们的患者情况一样,其通常表现为手臂、大腿和臀部的硬结性压痛斑块和结节。尽管绝大多数与皮肌炎相关的脂膜炎是亚临床的,且为偶然的组织病理学发现,但我们所呈现的病例进一步强调了有必要认识到脂膜炎是幼年皮肌炎某些皮损中一种罕见但具有临床相关性的病理特征。