Azevedo Paula de Oliveira, Castellen Natalia Roberta, Salai Ana Flávia, Barbosa Fernanda Santana, Alves Célia Antônia Xavier de Moraes, Pinto Clóvis Antonio Lopes
(Dermatology Service, Faculdade de Medicina de Jundiaí (FMJ) - Jundiaí (SP), Brasil.
Department of Pathology, Faculdade de Medicina de Jundiaí (FMJ) - Jundiaí (SP), Brasil.
An Bras Dermatol. 2018 Jan-Feb;93(1):119-121. doi: 10.1590/abd1806-4841.20186597.
Panniculitis is a rare clinical finding in dermatomyositis, with less than 30 cases reported and there is only one case associated with the amyopathic subtype described in the literature. The present report describes a 49-year-old female patient that one year after being diagnosed with amyopathic dermatomyositis, presented indurated, painful, erythematous to violaceous nodules located on the upper limbs, thighs and gluteal region. Skin biopsy revealed lobular panniculitis with a lymphocytic infiltrate. The patient was treated with prednisone and methotrexate, but remained unresponsive to treatment.
脂膜炎是皮肌炎中一种罕见的临床发现，报告的病例少于30例，文献中仅描述了1例与无肌病亚型相关的病例。本报告描述了一名49岁女性患者，在被诊断为无肌病性皮肌炎一年后，上肢、大腿和臀部出现硬结、疼痛、红斑至紫红色结节。皮肤活检显示小叶性脂膜炎伴淋巴细胞浸润。该患者接受了泼尼松和甲氨蝶呤治疗，但对治疗无反应。
