Lapointe J M, Hedges J F, Woods L W, Reubel G H, MacLachlan N J
Department of Pathology, Microbiology and Immunology, School of Veterinary Medicine, University of California, Davis, USA.
Arch Virol. 1999;144(2):393-6. doi: 10.1007/s007050050512.
DNA sequence data was obtained from an adenovirus previously shown to be the cause of a distinctive, fatal hemorrhagic disease of black-tailed deer in California. A 256 base fragment of the viral hexon gene was amplified by PCR from purified adenovirus preparations. The amplicon then was cloned and sequenced. Phylogenetic relationships with other mammalian adenoviruses were also determined. Although sequence analysis of this portion of the hexon gene indicates that the black-tailed deer adenovirus is closely related to bovine adenovirus-3, the biologic properties of the two viruses are clearly distinct.
DNA序列数据取自一种腺病毒，该腺病毒先前已被证明是加利福尼亚黑尾鹿一种独特的致命出血性疾病的病因。通过PCR从纯化的腺病毒制剂中扩增出病毒六邻体基因的一个256个碱基的片段。然后对扩增子进行克隆和测序。还确定了与其他哺乳动物腺病毒的系统发育关系。尽管对六邻体基因这一部分的序列分析表明，黑尾鹿腺病毒与牛腺病毒3密切相关，但这两种病毒的生物学特性明显不同。
