Sáez-Llorens X, McCracken G H
Department of Pediatrics, University of Panama School of Medicine, Panama City, Panama.
Infect Dis Clin North Am. 1999 Sep;13(3):619-36, vii. doi: 10.1016/s0891-5520(05)70097-0.
Mortality and morbidity rates of bacterial meningitis are still unacceptably high, and thus, new, potent antimicrobial agents and adjuvant anti-inflammatory strategies are being evaluated to improve patient outcome. With the declining rates of Haemophilus influenzae type B infections, after the introduction of conjugated vaccines, research to find preventive measures for Streptococcus pneumoniae and Neisseria meningitidis infections is underway. In the meantime, scientific effort is being directed optimally to treat disease caused by multiresistant pneumococcal strains.
细菌性脑膜炎的死亡率和发病率仍然高得令人难以接受，因此，正在评估新型强效抗菌药物和辅助抗炎策略，以改善患者预后。随着B型流感嗜血杆菌感染率在引入结合疫苗后下降，目前正在开展研究，以寻找预防肺炎链球菌和脑膜炎奈瑟菌感染的措施。与此同时，科研工作正以最佳方式致力于治疗由多重耐药肺炎球菌菌株引起的疾病。
