Lee Ji Eun, Cho Won Kyoung, Nam Chan Hee, Jung Min Ho, Kang Jin Han, Suh Byung Kyu
Department of Pediatrics, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Korean J Pediatr. 2010 May;53(5):653-6. doi: 10.3345/kjp.2010.53.5.653. Epub 2010 May 31.
Listeria monocytogenes is a facultative anaerobic, gram-positive bacillus that is isolated from the soil, vegetables, and wild or domestic animals. Listeria occurs predominantly in the elderly, immunocompromised patients, pregnant women and newborns. Infections by this microorganism are rare in healthy infants and children. L. monocytogenes may cause meningitis, meningoencephalitis, brain abscess, pyogenic arthritis, osteomyelitis, and liver abscesses in children. The course of meningoencephalitis by listeria is often severe and even fatal. Acute hydrocephalus can develop as a complication and the mortality associated with listeriosis is significantly high. We present a case of meningoencephalitis caused by L. monocytogenes in a previously healthy 7-year-old girl.
单核细胞增生李斯特菌是一种兼性厌氧的革兰氏阳性杆菌,可从土壤、蔬菜以及野生或家畜中分离出来。李斯特菌主要发生在老年人、免疫功能低下的患者、孕妇和新生儿中。这种微生物感染在健康婴儿和儿童中很少见。单核细胞增生李斯特菌可导致儿童脑膜炎、脑膜脑炎、脑脓肿、化脓性关节炎、骨髓炎和肝脓肿。李斯特菌引起的脑膜脑炎病程通常很严重,甚至会致命。急性脑积水可作为并发症出现,与李斯特菌病相关的死亡率显著较高。我们报告一例由单核细胞增生李斯特菌引起的脑膜脑炎病例,患者是一名此前健康的7岁女孩。