黑腹果蝇群体中的乙醇脱氢酶多态性。II. 乙醇脱氢酶活性与成虫死亡率之间的关系。
Alcohol dehydrogenase polymorphism in populations of Drosophila melanogaster. II. Relation between ADH activity and adult mortality.
作者信息
Kamping A, van Delden W
出版信息
Biochem Genet. 1978 Jun;16(5-6):541-51. doi: 10.1007/BF00484218.
PMID:104710
Abstract
Eight Drosophila melanogaster strains, seven homozygous for AdhF alleles and one for an Adh-null mutant, were compared for ADH activity in males and adult mortality on ethanol-supplemented food. The strains differed considerably in these qualities. A positive correlation was found between ADH activity and LD50. The relevance of this finding is discussed in relation to the differential selection acting on Adh genotypes kept on ethanol-supplemented food.
摘要
对八个黑腹果蝇品系进行了比较，其中七个为AdhF等位基因的纯合子，一个为Adh基因缺失突变体，比较了它们在雄性果蝇中的乙醇脱氢酶（ADH）活性以及在添加乙醇的食物上的成虫死亡率。这些品系在这些特性上有很大差异。发现ADH活性与半数致死剂量（LD50）之间存在正相关。结合对添加乙醇食物上的Adh基因型的差异选择，讨论了这一发现的相关性。
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