Fogassi L, Raos V, Franchi G, Gallese V, Luppino G, Matelli M
Istituto di Fisiologia Umana, Università di Parma, Via Volturno 39, I-43100 Parma, Italy,
Exp Brain Res. 1999 Sep;128(1-2):194-9. doi: 10.1007/s002210050835.
This study aimed to determine the presence of neurons responding to visual stimuli in area F2 of the dorsal premotor cortex of the macaque monkey. In order to delimit the sector in which visually responsive neurons are located, the somatotopic organization of area F2 was studied with intracortical microstimulation and single neuron recording. The results showed that: (1) in area F2 there is a significant percentage of visually responsive neurons (15.9% of all recorded neurons); (2) area F2 is excitable with a low-threshold current (average 28.1 microA) and has a somatotopic representation of the whole body, except the face; and (3) most visually driven neurons (n=130 out of 169) are concentrated within the rostrolateral sector of the forelimb representation of area F2, thus providing for the first time functional support for the neuroanatomical evidence that the visual input to area F2 is mostly restricted to this sector.
本研究旨在确定猕猴背侧运动前区皮质F2区中对视觉刺激有反应的神经元的存在情况。为了划定视觉反应神经元所在的区域，采用皮质内微刺激和单神经元记录的方法研究了F2区的躯体定位组织。结果表明：（1）在F2区，有相当比例的神经元对视觉刺激有反应（占所有记录神经元的15.9%）；（2）F2区可被低阈值电流激发（平均28.1微安），且除面部外，对全身有躯体定位表征；（3）大多数视觉驱动神经元（169个中有130个）集中在F2区前肢表征的 rostrolateral 区域内，从而首次为F2区的视觉输入大多局限于该区域这一神经解剖学证据提供了功能支持。
