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血小板反应蛋白在大鼠子宫妊娠早期依次表达,然后表达消失。

Thrombospondin is sequentially expressed and then de-expressed during early pregnancy in the rat uterus.

作者信息

Slater M, Murphy C R

机构信息

Department of Anatomy and Histology F13, The University of Sydney, NSW, Australia.

出版信息

Histochem J. 1999 Jul;31(7):471-5. doi: 10.1023/a:1003760026681.

Abstract

The expression of thrombospondin on Day 1, Day 3 and Day 6 of pregnancy has been examined in the rat, using light microscopic immunoperoxidase and electron immunogold techniques. The glycoprotein was expressed in the apical, lateral and basal uterine epithelium on Days 1 and 3 but was then de-expressed at the time of implantation on Day 6. We propose that these data suggest a role for thrombospondin in remodellig the uterine epithelium during the plasma membrane transformation, but that it does not play a part in attachment and implantation.

摘要

利用光学显微镜免疫过氧化物酶和电子免疫金技术,对大鼠孕期第1天、第3天和第6天的血小板反应蛋白表达情况进行了检测。该糖蛋白在第1天和第3天的子宫上皮顶端、侧面和基底均有表达,但在第6天着床时表达消失。我们认为,这些数据表明血小板反应蛋白在质膜转化过程中对子宫上皮重塑起作用,但在黏附和着床过程中不起作用。

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