Randomized prospective study of the influence of steroids on postoperative eye-opening after exploration of the orbital floor.

OBJECTIVE

To find out if giving steroids reduces postoperative swelling in orbital surgery.

DESIGN

Prospective, randomized, double-blind trial.

SETTING

Regional unit, teaching hospital, UK.

SUBJECTS AND INTERVENTIONS

20 patients who require orbital floor exploration after injuries. Patients were given methylprednisolone 250 mg (or placebo identically packaged) at induction of anaesthesia, with a further three doses at 6-hourly intervals postoperatively.

MAIN OUTCOME MEASURE

Differences in interpalpebral width before and after operation.

RESULTS

Those given steroids (n=11) had a significantly increased interpalpebral width compared with placebo (n=9) postoperatively (P < 0.01, 95% confidence intervals of the difference = 1 mm-6 mm).

CONCLUSION

Short courses of steroids therapy should be considered in orbital surgery for appropriate patients. There is an advantage in being able to assess the globe postoperatively.