高龄育龄女性绝育术后复通的生殖结局。
Reproductive outcome after sterilization reversal in women of advanced reproductive age.
作者信息
Cohen M A, Chang P L, Uhler M, Legro R, Sauer M V, Lindheim S R
机构信息
Department of Obstetrics and Gynecology, Columbia University College of Physicians & Surgeons, New York, New York 10032, USA.
出版信息
J Assist Reprod Genet. 1999 Sep;16(8):402-4. doi: 10.1023/a:1020509323039.
OBJECTIVE
Our objective was to assess the clinical outcome of tubal reversal in women of advanced reproductive age.
METHODS
A multicenter retrospective chart review of 153 patients who underwent a tubal ligation reversal was carried out. Patients were evaluated according to age. All patients had documented ovulation and a partner with a normal semen analysis by WHO criteria. Outcome measures included rates of clinical pregnancy, ectopic pregnancy, spontaneous abortion, and live birth, and the time to conception.
RESULTS
Clinical pregnancy rates were significantly lower in women > or = 40 compared to younger groups. The time to conception was significantly shorter for women < 30 compared to women > or = 35. No pregnancies occurred in women > or = 42.
CONCLUSIONS
Our data support the judicious use of sterilization reversal for infertile women with no male factor through their early forties. Women > or = 42 years should be especially counseled as to the very low success rates.
目的
我们的目的是评估高龄育龄妇女输卵管复通术的临床结局。
方法
对153例行输卵管结扎复通术的患者进行了多中心回顾性病历审查。根据年龄对患者进行评估。所有患者均有排卵记录，其配偶精液分析按世界卫生组织标准正常。结局指标包括临床妊娠率、异位妊娠率、自然流产率、活产率以及受孕时间。
结果
与年轻组相比，年龄≥40岁的女性临床妊娠率显著降低。与年龄≥35岁的女性相比，年龄<30岁的女性受孕时间显著缩短。年龄≥42岁的女性未发生妊娠。
结论
我们的数据支持在无男性因素的不孕妇女40岁出头之前审慎地进行绝育复通术。对于年龄≥42岁的女性，应特别告知其成功率极低。
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