环形泰勒虫感染山羊体内捻转血矛线虫成虫的交叉反应抗原
Cross-reactive antigens of Haemonchus contortus adult worms in Teladorsagia circumcincta infected goats.
作者信息
Molina J M, Ruiz A, Rodríguez-Ponce E, Gutiérrez A C, González J, Hernández S
机构信息
Departamento de Patología Animal (Parasitología y Enfermedades Parasitarias), Facultad de Veterinaria de la Universidad de Las Palmas de Gran Canaria, Grand Canary Island, Spain.
出版信息
Vet Res. 1999 Jul-Aug;30(4):393-9.
The adult Haemonchus contortus somatic antigens responsible for cross-reactivity have been analysed using serum samples from goat kids infected and reinfected with Teladorsagia circumcincta. Goat kids infected with T. circumcincta had similar serum ELISA values against somatic antigens of H. contortus as goats infected with H. contortus itself. Immunoblotting confirmed this extensive cross-reactivity particularly in the molecular weight range 105-29 kDa. However, peptides with high (195, 152 and 119 kDa) or low (23 kDa) molecular weight were only faintly recognized by heterologous sera.
利用感染并再次感染环纹奥斯特线虫的山羊羔血清样本，对导致交叉反应的成年捻转血矛线虫体抗原进行了分析。感染环纹奥斯特线虫的山羊羔针对捻转血矛线虫体抗原的血清ELISA值，与感染捻转血矛线虫本身的山羊相似。免疫印迹证实了这种广泛的交叉反应，特别是在分子量范围为105 - 29 kDa的区域。然而，高分子量（195、152和119 kDa）或低分子量（23 kDa）的肽仅被异种血清微弱识别。
Zotero 插件