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Synthesis and biophysical studies of modified oligonucleotides containing acyclic amino alcohol nucleoside analogs.

作者信息

Ramasamy K S, Stoisavljevic V

机构信息

Research Division, ICN Pharmaceuticals, Inc., Costa Mesa, CA 92626, USA.

出版信息

Nucleosides Nucleotides. 1999 Aug;18(8):1845-61. doi: 10.1080/07328319908044847.

DOI:10.1080/07328319908044847
PMID:10478486
Abstract

Novel serine derivative of thymine was prepared and incorporated into oligonucleotides. These modified oligonucleotides were studied for their binding affinity with complementary DNA/RNA.

摘要

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