用锝-99m六甲基丙二胺肟单光子发射计算机断层扫描（Tc-99m HMPAO SPECT）观察到甲状腺功能减退所致可逆性痴呆中的可逆性脑灌注不足。
Reversible cerebral hypoperfusion observed with Tc-99m HMPAO SPECT in reversible dementia caused by hypothyroidism.
作者信息
Kinuya S, Michigishi T, Tonami N, Aburano T, Tsuji S, Hashimoto T
机构信息
Department of Nuclear Medicine, Kanazawa University School of Medicine, Ishikawa, Japan.
出版信息
Clin Nucl Med. 1999 Sep;24(9):666-8. doi: 10.1097/00003072-199909000-00005.
A 69-year-old man had hypothyroid dementia as a result of I-131 therapy and an overdose of methimazole. Tc-99m HMPAO SPECT revealed diffuse cerebral hypoperfusion. The findings of brain SPECT normalized with the disappearance of symptoms and a return to the euthyroid state. There was a 25% or 26% reduction of the mean cerebral blood flow during dementia. This may be the first report in which SPECT brain imaging revealed reversible hypoperfusion associated with reversible hypothyroid dementia.
一名69岁男性因I-131治疗和甲巯咪唑过量导致甲状腺功能减退性痴呆。Tc-99m HMPAO SPECT显示弥漫性脑灌注不足。随着症状消失和甲状腺功能恢复正常，脑SPECT检查结果也恢复正常。痴呆期间平均脑血流量减少了25%或26%。这可能是首篇报道SPECT脑成像显示与可逆性甲状腺功能减退性痴呆相关的可逆性灌注不足的研究。
Zotero 插件