Zhang M, Rost K M, Fortney J C, Smith G R
Department of Veterans Affairs in Little Rock, Arkansas, USA.
Psychiatr Serv. 1999 Sep;50(9):1209-13. doi: 10.1176/ps.50.9.1209.
Although treatment for major depression has been shown to reduce the costs of lost earnings resulting from lost work days, research has not demonstrated whether the reduction fully offsets the costs of treatment for the disorder.
A statewide cohort of community residents with recent major depression, dysthymia, or substantial depressive symptoms was recruited and interviewed at baseline and at six-month and 12-month follow-ups. The cost of lost earnings was measured by lost work days multiplied by subjects' wage rates. Cost of treatment for depression was approximated using charges abstracted from provider and insurance records. Net economic cost, defined as the sum of changes in lost earnings and depression treatment costs, was examined in multiple regression analyses.
After the analyses controlled for sociodemographic characteristics, baseline severity of depression, and comorbidity, no statistically significant effect of depression treatment on net economic cost was found. This finding suggests that the cost of depression treatment was fully offset by savings from reduction in lost work days. Results from sensitivity analyses in multiple alternative scenarios support the same conclusion.
The finding of a full offset of depression treatment cost is conservative because other benefits, such as reduced pain and suffering and increased productivity while at work, were not included in the analyses. Employers who bear the cost from lost work days should encourage their employees with depressive disorders to seek treatment, even if it means paying for the entire treatment cost. Self-employed individuals with depression also will benefit even if they pay for the treatment costs themselves.
尽管已证明重度抑郁症的治疗可降低因工作日损失而导致的收入损失成本,但研究尚未表明这种降低是否能完全抵消该疾病的治疗成本。
招募了一个全州范围内近期患有重度抑郁症、心境恶劣或有明显抑郁症状的社区居民队列,并在基线、六个月和十二个月随访时进行访谈。收入损失成本通过工作日损失乘以受试者的工资率来衡量。抑郁症治疗成本使用从医疗服务提供者和保险记录中提取的费用进行估算。在多元回归分析中考察了净经济成本,净经济成本定义为收入损失和抑郁症治疗成本变化的总和。
在分析控制了社会人口学特征、抑郁症基线严重程度和合并症后,未发现抑郁症治疗对净经济成本有统计学上的显著影响。这一发现表明,抑郁症治疗成本被工作日损失减少带来的节省完全抵消。多种替代情景下的敏感性分析结果支持相同结论。
抑郁症治疗成本完全抵消这一发现是保守的,因为分析中未包括其他益处,如减轻痛苦和提高工作时的生产力。承担工作日损失成本的雇主应鼓励患有抑郁症的员工寻求治疗,即使这意味着支付全部治疗费用。患有抑郁症的个体经营者即使自行支付治疗费用也将受益。