Dowdy S C, Pfeifer E A, Longcope D C, Cliby W A
Department of Obstetrics and Gynecology, Laboratory Medicine and Pathology, Mayo Clinic and Mayo Foundation, Rochester, Minnesota, 55905, USA.
Gynecol Oncol. 1999 Sep;74(3):495-8. doi: 10.1006/gyno.1999.5465.
Ovarian carcinomas typically metastasize to multiple sites via exfoliation, lymphatic spread, or direct invasion. Gastrointestinal tract involvement is usually the result of exfoliation with direct invasion of tumor within the mesentery or through serosal surfaces. We present a case of late recurrence of ovarian carcinoma isolated to the sigmoid mucosa, heralded only by brief left lower quadrant pain with hematochezia in a patient otherwise disease free for 9 years. This unusual presentation illustrates the therapeutic dilemma faced by clinicians when a tumor is of uncertain origin and underscores the need for continued follow-up and close scrutiny of new symptoms in patients with stage I disease and for those who enjoy prolonged disease-free intervals.
卵巢癌通常通过脱落、淋巴转移或直接侵犯等方式转移至多个部位。胃肠道受累通常是肿瘤脱落后直接侵犯肠系膜内或通过浆膜表面所致。我们报告一例卵巢癌晚期复发,仅局限于乙状结肠黏膜,表现为一名9年无病的患者仅出现短暂的左下腹疼痛伴便血。这种不寻常的表现说明了当肿瘤起源不明时临床医生所面临的治疗困境,并强调了对I期疾病患者以及那些有较长无病间期的患者进行持续随访和密切观察新症状的必要性。