Kurokawa T, Suzuki S, Kawaguchi K, Fujisawa N, Yoshimura N
Department of Ophthalmology, Shinshu University School of Medicine, Matsumoto, Japan.
Am J Ophthalmol. 1999 Jul;128(1):114-6. doi: 10.1016/s0002-9394(99)00027-6.
To describe a patient with multicentric Castleman disease who was initially examined with ophthalmic signs and symptoms.
Case report. A 71-year-old man was initially examined with swelling of both upper eyelids and diplopia of 2 months' duration.
Medical evaluation and right axillary lymph node biopsy disclosed Castleman disease. Systemic corticosteroid treatment temporarily resolved signs and symptoms, but the patient died of recurrence with cytomegalovirus and Aspergillus infection 10 months after initial examination.
Multicentric Castleman disease is a rare but distinct disorder that may present initially with ocular signs and symptoms. This disease must be included in the differential diagnosis of orbital pseudotumor and lymphoma.
描述一名最初因眼科体征和症状接受检查的多中心Castleman病患者。
病例报告。一名71岁男性最初因双眼上睑肿胀和持续2个月的复视而接受检查。
医学评估和右腋窝淋巴结活检确诊为Castleman病。全身皮质类固醇治疗暂时缓解了体征和症状，但患者在初次检查10个月后因巨细胞病毒和曲霉菌感染复发而死亡。
多中心Castleman病是一种罕见但独特的疾病，最初可能表现为眼部体征和症状。这种疾病必须列入眼眶假瘤和淋巴瘤的鉴别诊断中。
