Lee E C, Papaioannou N
Ann R Coll Surg Engl. 1982 Jul;64(4):229-33.
Patients with extensive chronic Crohn's disease of the small bowel, who may have had repeated excisional surgery, sometimes develop intestinal obstruction due to the development of a stricture. Surgery is usually thought to be contraindicated since further resections would leave the patient with insufficient small intestine to maintain a normal state of nutrition. Nine such patients have been treated since 1979 by operations which have been designed simply to relieve the obstruction. After careful preparation with intravenous alimentation, clearing the intestine of its contents, and the use of prophylactic antibodies the strictures were treated with minimal excisions, enteroenterostomies, and 'strictureplasties' according to their length and the degree of inflammation. In spite of the apparent danger of carrying out the operations through active Crohn's inflammation there have been no fatalities or major complications and the long-term results have been good.
患有广泛小肠慢性克罗恩病的患者,可能已经接受过多次切除手术,有时会因狭窄形成而发生肠梗阻。由于进一步切除会使患者剩余的小肠不足以维持正常营养状态,手术通常被认为是禁忌的。自1979年以来,已有9名此类患者接受了旨在缓解梗阻的手术。在通过静脉营养进行仔细准备、清空肠道内容物并使用预防性抗体后,根据狭窄的长度和炎症程度,对狭窄进行了最小限度的切除、肠吻合术和“狭窄成形术”。尽管在活动性克罗恩炎症情况下进行手术存在明显风险,但并未出现死亡或重大并发症,长期效果良好。