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炎症性肠病再次手术

Reoperative inflammatory bowel disease surgery.

作者信息

Ramirez Rowena L, Fleshner Phillip

机构信息

Division of Colorectal Surgery, Cedars-Sinai Medical Center, Los Angeles, California, USA.

出版信息

Clin Colon Rectal Surg. 2006 Nov;19(4):195-206. doi: 10.1055/s-2006-956440.

Abstract

With the advent of restorative proctocolectomy or ileal pouch-anal anastomosis (IPAA) for ulcerative colitis (UC), not only has there been potential for cure of UC but also patients have enjoyed marked improvements in bowel function, continence, and quality of life. However, IPAA can be complicated by postoperative small bowel obstruction, disease recurrence, and pouch failure secondary to pelvic sepsis, pouch dysfunction, mucosal inflammation, and neoplastic transformation. These may necessitate emergent or expeditious elective reoperation to salvage the pouch and preserve adequate function. Local, transanal, and transabdominal approaches to IPAA salvage are described, and their indications, outcomes, and the clinical parameters that affect the need for salvage are discussed. Pouch excision for failed salvage reoperation is reviewed as well. Relaparotomy is also frequently required for recurrent Crohn's disease (CD), especially given the nature of this as yet incurable illness. Risk factors for CD recurrence are examined, and the various surgical options and margins of resection are evaluated with a focus on bowel-sparing policy. Stricturoplasty, its outcomes, and its importance in recurrent disease are discussed, and segmental resection is compared with more extensive procedures such as total colectomy with ileorectal anastomosis. Lastly, laparoscopy is addressed with respect to its long-term outcomes, effect on surgical recurrence, and its application in the management of recurrent CD.

摘要

随着溃疡性结肠炎(UC)的恢复性直肠结肠切除术或回肠储袋肛管吻合术(IPAA)的出现,不仅UC有可能治愈,而且患者的肠道功能、控便能力和生活质量也有了显著改善。然而,IPAA可能会出现术后小肠梗阻、疾病复发以及盆腔脓毒症、储袋功能障碍、黏膜炎症和肿瘤转化导致的储袋功能衰竭等并发症。这些可能需要紧急或迅速进行择期再次手术以挽救储袋并保留足够的功能。本文描述了IPAA挽救手术的局部、经肛门和经腹入路,并讨论了其适应证、结果以及影响挽救手术需求的临床参数。还回顾了挽救性再次手术失败后的储袋切除术。再次剖腹手术对于复发性克罗恩病(CD)也经常是必要的,特别是考虑到这种疾病目前仍无法治愈的性质。研究了CD复发的危险因素,并评估了各种手术选择和切除边缘,重点是保留肠管的策略。讨论了狭窄成形术及其结果以及在复发性疾病中的重要性,并将节段性切除与更广泛的手术如全结肠切除回肠直肠吻合术进行了比较。最后,讨论了腹腔镜手术的长期结果、对手术复发的影响及其在复发性CD管理中的应用。

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