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Pneumocystis carinii carriage in immunocompetent patients with primary pulmonary disorders as detected by single or nested PCR.通过单重或巢式聚合酶链反应检测免疫功能正常的原发性肺部疾病患者中的卡氏肺孢子虫携带情况。
J Clin Microbiol. 1999 Oct;37(10):3409-10. doi: 10.1128/JCM.37.10.3409-3410.1999.
2
Pneumocystis carinii carriage in immunocompromised patients with and without human immunodeficiency virus infection.卡氏肺孢子虫在合并或未合并人类免疫缺陷病毒感染的免疫功能低下患者中的携带情况。
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Evaluation of diagnostic value and epidemiological implications of PCR for Pneumocystis carinii in different immunosuppressed and immunocompetent patient groups.评价聚合酶链反应（PCR）检测不同免疫抑制和免疫功能正常患者组卡氏肺孢子虫的诊断价值及流行病学意义。
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The role of acute and chronic respiratory colonization and infections in the pathogenesis of COPD.急慢性呼吸道定植和感染在慢性阻塞性肺疾病发病机制中的作用。
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本文引用的文献

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Pneumocystis carinii colonization in the absence of immunosuppression.在无免疫抑制情况下的卡氏肺孢子虫定植。
Scand J Infect Dis. 1997;29(6):591-3. doi: 10.3109/00365549709035900.
2
Detection of Pneumocystis carinii among children with chronic respiratory disorders in the absence of HIV infection and immunodeficiency.在无HIV感染和免疫缺陷的慢性呼吸道疾病儿童中检测卡氏肺孢子虫。
J Med Microbiol. 1998 Apr;47(4):329-33. doi: 10.1099/00222615-47-4-329.
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Gapped BLAST and PSI-BLAST: a new generation of protein database search programs.空位BLAST和位置特异性迭代BLAST：新一代蛋白质数据库搜索程序。
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Correlation of Pneumocystis carinii PCR with clinical diagnosis in immunocompromised patients.卡氏肺孢子虫聚合酶链反应与免疫功能低下患者临床诊断的相关性
Lancet. 1996 May 4;347(9010):1266. doi: 10.1016/s0140-6736(96)90787-4.
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Pneumocystis carinii infection in patients with chronic bronchial disease.慢性支气管疾病患者的卡氏肺孢子虫感染
Lancet. 1996 Apr 6;347(9006):977. doi: 10.1016/s0140-6736(96)91468-3.
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Pneumocystis carinii in lungs of adults at autopsy.成人尸检肺组织中的卡氏肺孢子虫。
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Pneumocystis carinii pneumonia.卡氏肺孢子虫肺炎
Ann Intern Med. 1968 Jan;68(1):97-108. doi: 10.7326/0003-4819-68-1-97.
8
Observations favouring Pneumocystis carinii pneumonia as a primary infection: a monoclonal antibody study on paraffin sections.支持卡氏肺孢子虫肺炎作为原发性感染的观察结果：石蜡切片的单克隆抗体研究
J Pathol. 1988 Apr;154(4):365-70. doi: 10.1002/path.1711540413.
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Detection of Pneumocystis carinii with DNA amplification.采用DNA扩增技术检测卡氏肺孢子虫。
Lancet. 1990 Aug 25;336(8713):451-3. doi: 10.1016/0140-6736(90)92008-6.
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A search for Pneumocystis carinii in post-mortem lungs by DNA amplification.通过DNA扩增法在尸检肺组织中检测卡氏肺孢子虫。
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通过单重或巢式聚合酶链反应检测免疫功能正常的原发性肺部疾病患者中的卡氏肺孢子虫携带情况。

Pneumocystis carinii carriage in immunocompetent patients with primary pulmonary disorders as detected by single or nested PCR.

作者信息

Sing A, Roggenkamp A, Autenrieth I B, Heesemann J

机构信息

Max von Pettenkofer-Institut für Hygiene und Medizinische Mikrobiologie, Munich, Germany.

出版信息

J Clin Microbiol. 1999 Oct;37(10):3409-10. doi: 10.1128/JCM.37.10.3409-3410.1999.

DOI:10.1128/JCM.37.10.3409-3410.1999
PMID:10488221
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC85586/
Abstract

Ninety-five bronchoalveolar lavage specimens from 63 immunocompetent adult patients with primary pulmonary disease were analyzed for Pneumocystis carinii colonization by primary and nested PCR. Twelve of 63 patients (19%) were PCR positive. None of them developed P. carinii pneumonia. These results suggest that P. carinii carriage may exist in immunocompetent patients with underlying pulmonary disease.

摘要

对63例患有原发性肺部疾病的免疫功能正常的成年患者的95份支气管肺泡灌洗标本，采用初次PCR和巢式PCR分析卡氏肺孢子虫定植情况。63例患者中有12例（19%）PCR呈阳性。他们均未发生卡氏肺孢子虫肺炎。这些结果表明，患有潜在肺部疾病的免疫功能正常患者中可能存在卡氏肺孢子虫携带情况。