通过单重或巢式聚合酶链反应检测免疫功能正常的原发性肺部疾病患者中的卡氏肺孢子虫携带情况。
Pneumocystis carinii carriage in immunocompetent patients with primary pulmonary disorders as detected by single or nested PCR.
作者信息
Sing A, Roggenkamp A, Autenrieth I B, Heesemann J
机构信息
Max von Pettenkofer-Institut für Hygiene und Medizinische Mikrobiologie, Munich, Germany.
出版信息
J Clin Microbiol. 1999 Oct;37(10):3409-10. doi: 10.1128/JCM.37.10.3409-3410.1999.
Abstract
Ninety-five bronchoalveolar lavage specimens from 63 immunocompetent adult patients with primary pulmonary disease were analyzed for Pneumocystis carinii colonization by primary and nested PCR. Twelve of 63 patients (19%) were PCR positive. None of them developed P. carinii pneumonia. These results suggest that P. carinii carriage may exist in immunocompetent patients with underlying pulmonary disease.
摘要
对63例患有原发性肺部疾病的免疫功能正常的成年患者的95份支气管肺泡灌洗标本，采用初次PCR和巢式PCR分析卡氏肺孢子虫定植情况。63例患者中有12例（19%）PCR呈阳性。他们均未发生卡氏肺孢子虫肺炎。这些结果表明，患有潜在肺部疾病的免疫功能正常患者中可能存在卡氏肺孢子虫携带情况。
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