Dani C, Reali M F, Bertini G, Wiechmann L, Spagnolo A, Tangucci M, Rubaltelli F F
Division of Neonatology, Careggi University Hospital of Florence, Italy.
Eur Respir J. 1999 Jul;14(1):155-9. doi: 10.1034/j.1399-3003.1999.14a26.x.
Respiratory distress syndrome (RDS) and transient tachypnoea (TT) are the most frequent acute respiratory diseases in the newborn. This study investigated the risk factors for RDS and TT in newborn infants. A population of 63,537 newborns was enrolled in a 12-month survey in Italy, 734 (1.15%) affected by RDS and 594 (0.93%) affected by TT. Multivariate regression analysis of maternal and perinatal data and the calculation of odds ratios (with 95% confidence intervals) were performed. It was demonstrated that gestational age, birthweight, maternal age, elective and emergency caesarean section (CS), and male sex were risk factors for RDS, while gestational age, maternal diseases, twinning, birthweight, operative vaginal delivery, elective and emergency CS, and male sex were risk factors for TT. The data confirm previous reports and demonstrate that advanced maternal age is a risk factor for RDS, while ruling out maternal diseases as independent risk factors for RDS.
呼吸窘迫综合征（RDS）和短暂性呼吸急促（TT）是新生儿中最常见的急性呼吸道疾病。本研究调查了新生儿RDS和TT的危险因素。在意大利进行的一项为期12个月的调查中，纳入了63537名新生儿，其中734名（1.15%）患有RDS，594名（0.93%）患有TT。对母亲和围产期数据进行了多变量回归分析，并计算了比值比（95%置信区间）。结果表明，胎龄、出生体重、母亲年龄、择期和急诊剖宫产以及男性性别是RDS的危险因素，而胎龄、母亲疾病、双胎妊娠、出生体重、阴道助产、择期和急诊剖宫产以及男性性别是TT的危险因素。这些数据证实了先前的报道，并表明母亲年龄较大是RDS的危险因素，同时排除了母亲疾病作为RDS的独立危险因素。
