French L E, Piletta P A, Etienne A, Salomon D, Saurat J H
Department of Dermatology/DHURDV, HCU, Geneva, Switzerland.
Dermatology. 1999;198(4):410-1.
Grovers's disease may be triggered by bed rest.
We have prospectively analyzed, over a 30-month period, all cases of transient acantholytic dermatosis (TAD) diagnosed in the context of a dermatological consultation for inpatients of a community hospital.
A total of 28 cases of TAD were diagnosed within a total of 3,750 patients examined (0.8%). The mean age of patients with TAD was 66.7 years, and the male-to-female ratio was 1.8. In 83% of cases the length of hospitalization preceding TAD was 66.7 years, and the male-to-female ratio was 1.8. In 83% of cases the length of hospitalization preceding TAD exceeded 2 weeks, and in all cases there was an association with strict bed rest. No association with malignant disease or other specific pathologies was observed.
Our results suggest that TAD, which is frequent in elderly patients within a hospital setting, is not paraneoplastic and favor the hypothesis of a sweat-related pathogenesis.
格罗弗病可能由卧床休息引发。
我们对一家社区医院住院患者皮肤科会诊中诊断出的所有暂时性棘层松解性皮肤病（TAD）病例进行了为期30个月的前瞻性分析。
在总共3750例接受检查的患者中，共诊断出28例TAD（0.8%）。TAD患者的平均年龄为66.7岁，男女比例为1.8。在83%的病例中，TAD出现前的住院时间超过2周，并且在所有病例中均与严格卧床休息有关。未观察到与恶性疾病或其他特定病理的关联。
我们的结果表明，TAD在医院环境中的老年患者中很常见，不是副肿瘤性的，支持与出汗相关的发病机制假说。
