Boutli Fotini, Voyatzi Maria, Lefaki Ioanna, Chaidemenos Giorgos, Kanitakis Jean
Skin and Venereal Diseases Hospital State Department, Thessaloniki, Greece.
J Dermatol. 2006 Mar;33(3):178-81. doi: 10.1111/j.1346-8138.2006.00041.x.
Grover's disease ("transient acantholytic dermatosis") is a transient dermatosis of unknown cause manifesting clinically as a papular skin eruption located usually on the anterior chest and abdomen and histologically with dyskeratosis and acantholysis. Grover's disease has occasionally been reported in patients with chronic renal failure, HIV infection, hematological malignancies and bone-marrow allotransplantation. We report herein a new case of Grover's disease that developed in a renal transplant patient. To the best of our knowledge, this is the first observation of Grover's disease developing in the setting of solid organ transplantation.
格罗弗病(“暂时性棘层松解性皮病”)是一种病因不明的暂时性皮肤病,临床症状表现为通常位于前胸和腹部的丘疹性皮疹,组织学表现为角化不良和棘层松解。格罗弗病偶尔在慢性肾衰竭、HIV感染、血液系统恶性肿瘤和骨髓同种异体移植患者中被报道。我们在此报告一例肾移植患者发生格罗弗病的新病例。据我们所知,这是实体器官移植背景下发生格罗弗病的首次观察报告。