Leclercq C, Berardi D, Sorbillo M R, Lambe J
National Institute of Nutrition, Rome, Italy.
Food Addit Contam. 1999 Mar;16(3):99-109. doi: 10.1080/026520399284145.
The intake of saccharin, aspartame, acesulfame K and cyclamate was assessed in 212 Italian teenagers aged 13-19 in 1996. Total daily intake of intense sweeteners was assessed on the basis of dietary records (14 consecutive days). The sweetener content of sugar-free products (soft drinks, candies, chewing gums, yoghurts, jam and table-top sweeteners) was provided by manufacturers. Sugar-free products were consumed by 77% of the subjects. Mean daily intake among consumers was 0.24 mg/kg body weight (bw) for cyclamate (13 subjects), 0.21 mg/kg bw for saccharin (9 subjects), 0.03 mg/kg bw for aspartame (162 subjects), and 0.02 mg/kg bw for acesulfame K (56 subjects). No subject exceeded the ADI (Acceptable Daily Intake) of an intense sweetener. Projections based on the present levels of use of intense sweeteners in sugar-free products and on the dietary pattern observed in the sample suggest that approaching the ADI could be possible only if subjects with high intakes of both soft drinks and table-top sugar substituted these items with respectively sugar-free beverages and table-top sweeteners containing either saccharin or cyclamate.
1996年，对212名年龄在13至19岁的意大利青少年的糖精、阿斯巴甜、安赛蜜和甜蜜素摄入量进行了评估。基于饮食记录（连续14天）评估了高强度甜味剂的每日总摄入量。无糖产品（软饮料、糖果、口香糖、酸奶、果酱和餐桌甜味剂）的甜味剂含量由制造商提供。77%的受试者食用了无糖产品。消费者中甜蜜素的平均每日摄入量为0.24毫克/千克体重（bw）（13名受试者），糖精为0.21毫克/千克bw（9名受试者），阿斯巴甜为0.03毫克/千克bw（162名受试者），安赛蜜为0.02毫克/千克bw（56名受试者）。没有受试者超过高强度甜味剂的每日允许摄入量（ADI）。根据无糖产品中高强度甜味剂的当前使用水平以及样本中观察到的饮食模式进行预测，只有当软饮料和餐桌糖摄入量高的受试者分别用含糖精或甜蜜素的无糖饮料和餐桌甜味剂替代这些食品时，才有可能接近每日允许摄入量。
