Faculty of Pharmacy, Group of Bromatology, CEF, University of Coimbra, Coimbra, Portugal.
Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2008 Nov;25(11):1291-6. doi: 10.1080/02652030802195309.
In a survey of levels of acesulfame-K and aspartame in soft drinks and in light nectars, the intake of these intense sweeteners was estimated for a group of teenage students. Acesulfame-K was detected in 72% of the soft drinks, with a mean concentration of 72 mg l(-1) and aspartame was found in 92% of the samples with a mean concentration of 89 mg l(-1). When data on the content of these sweeteners in soft drinks were analysed according to flavour, cola drinks had the highest mean levels for both sweeteners with 98 and 103 mg l(-1) for acesulfame-K and aspartame, respectively. For soft drinks based on mineral water, aspartame was found in 62% of the samples, with a mean concentration of 82 mg l(-1) and acesulfame-K was found in 77%, with a mean level of 48 mg l(-1). All samples of nectars contained acesulfame-K, with a mean concentration of 128 mg l(-1) and aspartame was detected in 80% of the samples with a mean concentration of 73 mg l(-1). A frequency questionnaire, designed to identify adolescents having high consumption of these drinks, was completed by a randomly selected sample of teenagers (n = 65) living in the city of Coimbra, in 2007. The estimated daily intakes (EDI) of acesulfame-K and aspartame for the average consumer were below the acceptable daily intakes (ADIs). For acesulfame-K, the EDI was 0.7 mg kg(-1) bw day(-1) for soft drinks, 0.2 mg kg(-1) bw day(-1) for soft drinks based on mineral waters, and 0.5 mg kg(-1) bw day(-1) for nectars, representing 8.0%, 2.2%, and 5.8% of the ADI, respectively. A similar situation was observed for aspartame. In this way, the EDI for soft drinks was 1.1 mg kg(-1) day(-1), representing only 2.9% of the ADI. In respect of nectars, the EDI was 0.2 mg kg(-1) bw day(-1), representing 0.5% of the ADI. Soft drinks based on mineral waters showed the lowest EDI values of 0.3 mg kg(-1) bw day(-1), accounting for 0.7% of the ADI.
在一项关于软饮料和淡花蜜中乙酰磺胺酸钾和阿斯巴甜含量的调查中，研究人员估算了一组青少年学生对这些高强度甜味剂的摄入量。在 72%的软饮料中检测到乙酰磺胺酸钾，平均浓度为 72mg/L；在 92%的样本中发现了阿斯巴甜，平均浓度为 89mg/L。当根据风味分析软饮料中这些甜味剂的含量数据时，可乐饮料中这两种甜味剂的平均含量最高，分别为乙酰磺胺酸钾 98mg/L 和阿斯巴甜 103mg/L。对于基于矿泉水的软饮料，62%的样本中含有阿斯巴甜，平均浓度为 82mg/L，77%的样本中含有乙酰磺胺酸钾，平均浓度为 48mg/L。所有花蜜样本均含有乙酰磺胺酸钾，平均浓度为 128mg/L，80%的样本中检测到阿斯巴甜，平均浓度为 73mg/L。2007 年，研究人员设计了一份频率调查问卷，以识别有高消费这些饮料习惯的青少年，并由随机选择的居住在科英布拉市的青少年（n=65）完成。对于普通消费者，乙酰磺胺酸钾和阿斯巴甜的日估计摄入量（EDI）低于可接受日摄入量（ADI）。对于乙酰磺胺酸钾，软饮料的 EDI 为 0.7mg/kg bw/day，软饮料矿泉水基础饮料的 EDI 为 0.2mg/kg bw/day，花蜜的 EDI 为 0.5mg/kg bw/day，分别占 ADI 的 8.0%、2.2%和 5.8%。阿斯巴甜的情况类似。在这种情况下，软饮料的 EDI 为 1.1mg/kg bw/day，仅占 ADI 的 2.9%。至于花蜜，EDI 为 0.2mg/kg bw/day，占 ADI 的 0.5%。矿泉水基础软饮料的 EDI 值最低，为 0.3mg/kg bw/day，占 ADI 的 0.7%。
