Colon G P, Deveikis J P, Dickinson L D
Department of Surgery, University of Michigan Hospitals, Ann Arbor, USA.
Neurosurgery. 1999 Sep;45(3):634-7. doi: 10.1097/00006123-199909000-00040.
The vasa vasorum are involved in the pathophysiological development of carotid artery atherosclerosis, providing vascular support to the thickened intima and plaque. When advanced atherosclerosis causes carotid artery occlusion, the vasa vasorum may serve as a means of revascularization.
We studied four patients with internal carotid artery occlusion who exhibited revascularization, distal to the occlusion, by small vascular channels that were inconsistent with recanalization through the thrombus. The channels had an angiographic appearance consistent with their being hypertrophied vasa vasorum. Significant collateral circulation was provided by the revascularization.
All four patients exhibited adequate collateral circulation and were treated with antiplatelet or anticoagulation medication.
The vasa vasorum have not been previously reported to contribute to the revascularization of occluded arteries. The four cases presented in this report suggest that the vasa vasorum can be a source of collateral circulation after carotid artery occlusion secondary to atherosclerotic disease.
血管滋养血管参与颈动脉粥样硬化的病理生理发展过程，为增厚的内膜和斑块提供血管支持。当晚期动脉粥样硬化导致颈动脉闭塞时，血管滋养血管可能成为一种血管再通的方式。
我们研究了4例颈内动脉闭塞患者，这些患者在闭塞远端通过与血栓再通不一致的小血管通道实现了血管再通。这些通道的血管造影表现与其为肥大的血管滋养血管一致。血管再通提供了显著的侧支循环。
所有4例患者均表现出足够的侧支循环，并接受了抗血小板或抗凝药物治疗。
此前尚未报道血管滋养血管有助于闭塞动脉的血管再通。本报告中呈现的4例病例表明，血管滋养血管可能是动脉粥样硬化疾病继发颈动脉闭塞后侧支循环的一个来源。
