Ho K Y, Yeoh K G, Kang J Y
Department of Medicine, National University of Singapore, Singapore.
Ann Acad Med Singap. 1999 Mar;28(2):189-92.
Data on oesophageal manometry in normal subjects in the East are limited. The aim of this study was to define standard oesophageal pressure values in a group of healthy adults in Singapore. Standard oesophageal manometry was performed on 26 asymptomatic volunteers (12 males and 14 females, aged 19 to 34 years) using the water-perfused capillary system and stationary pull-through technique. Median (range) lower oesophageal sphincter pressure, distal oesophageal contractile amplitude, distal oesophageal contractile duration and distal oesophageal contractile velocity were 13.6 (8.0 to 32.0) mmHg, 93.0 (41.0 to 143.0) mmHg, 3.8 (3.2 to 5.3) s and 3.6 (2.2 to 4.6) cm/s respectively. They were similar in males and females except for distal oesophageal contractile velocity which was higher in males than females [4.0 (3.1 to 4.6) cm/s versus 3.2 (2.2 to 4.4) cm/s, P < 0.01]. They were also generally in line with published normal values from Western countries. The present study helps to establish standards for normal manometric findings, at least among the young adults, in this part of the world.
东方正常受试者的食管测压数据有限。本研究的目的是确定一组新加坡健康成年人的标准食管压力值。使用水灌注毛细管系统和固定牵拉技术，对26名无症状志愿者（12名男性和14名女性，年龄19至34岁）进行标准食管测压。食管下括约肌压力中位数（范围）、食管远端收缩幅度、食管远端收缩持续时间和食管远端收缩速度分别为13.6（8.0至32.0）mmHg、93.0（41.0至143.0）mmHg、3.8（3.2至5.3）秒和3.6（2.2至4.6）cm/s。除食管远端收缩速度男性高于女性外[4.0（3.1至4.6）cm/s对3.2（2.2至4.4）cm/s，P<0.01]，男性和女性的这些指标相似。它们也总体上与西方国家公布的正常值一致。本研究有助于建立世界这一地区正常测压结果的标准，至少在年轻人中是这样。
