Blotta M H, Mamoni R L, Oliveira S J, Nouér S A, Papaiordanou P M, Goveia A, Camargo Z P
Department of Clinical Pathology, Faculty of Medical Sciences, State University of Campinas, SP, Brazil.
Am J Trop Med Hyg. 1999 Sep;61(3):390-4. doi: 10.4269/ajtmh.1999.61.390.
This paper describes the clinical-seroepidemiologic characteristics of patients with paracoccidioidomycosis (PCM) who visited the University Hospital at the State University of Campinas (Campinas, Sao Paulo, Brazil). The study group consisted of 584 individuals (492 males and 92 females) with ages ranging from 5 to 87 years. The highest incidence of the disease occurred between the ages of 41 and 50 years for men and between 11 and 40 years for women. Rural activities were the principal occupation of 46% of the patients. The diagnosis was confirmed by histopathologic examination and demonstration of fungus in scrapings, secretions, or in the sputum. Serologic test results for PCM were positive in 80% of the 584 patients studied. The significant number of patients, including 33 children less than 14 years old, indicates the presence of the fungus in the area and that this region is an important endemic area for PCM.
本文描述了前往巴西圣保罗坎皮纳斯州立大学大学医院就诊的副球孢子菌病（PCM）患者的临床血清流行病学特征。研究组由584名个体组成（492名男性和92名女性），年龄在5至87岁之间。该疾病的最高发病率在男性41至50岁之间以及女性11至40岁之间出现。农村活动是46%患者的主要职业。诊断通过组织病理学检查以及在刮片、分泌物或痰液中发现真菌得以证实。在584名研究患者中，80%的PCM血清学检测结果呈阳性。大量患者，包括33名14岁以下儿童，表明该地区存在这种真菌，且该区域是PCM的一个重要流行地区。
