Department of Internal Medicine, Division of Infectious Disease, UC Davis Medical Center, Sacramento, CA, USA; Department of Medical Microbiology and Immunology, University of California, Davis, CA, USA.
Division of Infectious Diseases and International Health, Duke University School of Medicine, Durham, NC, USA; Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.
Lancet Infect Dis. 2021 Dec;21(12):e364-e374. doi: 10.1016/S1473-3099(21)00191-2. Epub 2021 Aug 6.
The global burden of the endemic mycoses (blastomycosis, coccidioidomycosis, emergomycosis, histoplasmosis, paracoccidioidomycosis, sporotrichosis, and talaromycosis) continues to rise yearly and these infectious diseases remain a leading cause of patient morbidity and mortality worldwide. Management of the associated pathogens requires a thorough understanding of the epidemiology, risk factors, diagnostic methods and performance characteristics in different patient populations, and treatment options unique to each infection. Guidance on the management of these infections has the potential to improve prognosis. The recommendations outlined in this Review are part of the "One World, One Guideline" initiative of the European Confederation of Medical Mycology. Experts from 23 countries contributed to the development of these guidelines. The aim of this Review is to provide an up-to-date consensus and practical guidance in clinical decision making, by engaging physicians and scientists involved in various aspects of clinical management.
地方性真菌病（芽生菌病、球孢子菌病、粗球孢子菌病、组织胞浆菌病、副球孢子菌病、孢子丝菌病和足放线病菌病）的全球负担每年持续增加，这些传染病仍然是全球患者发病率和死亡率的主要原因。相关病原体的管理需要深入了解流行病学、危险因素、不同患者人群中的诊断方法和性能特征，以及每种感染特有的治疗选择。有关这些感染管理的指南有可能改善预后。本综述中概述的建议是欧洲医学真菌学联合会“一个世界，一个指南”倡议的一部分。来自 23 个国家的专家为制定这些指南做出了贡献。本综述的目的是通过让参与临床管理各个方面的医生和科学家参与进来，就临床决策提供最新的共识和实用指南。
