Brzezińska-Wcisło L
I Katedry i Kliniki Dermatologii Slaskiej Akademii Medycznej w Katowicach.
Wiad Lek. 1999;52(3-4):168-73.
Acne vulgaris, the most frequent skin disease of adolescence, because of its location, particularly long lasting course and in, case of some patients, leaving deformations in a form of scars can lead to disturbances in the psychosocial sphere. Medications used in the topical and systemic therapy of acne should reveal such proportions as: anti-seborrhoeic, bactericidal, bacteriostatic, antiphogistic, comedoleitis, anti-comedoformative. Both, in the topical and systemic therapy of acne vulgaris antibiotics such as tetracyclines, erythromycin and clindamycin are used. Other medicaments prescribed for the topical therapy of acne are azelaic acid and benzoil peroxide, retinoic acid--tretinoin and 13-cis-Retinoic acid--isotretinoin. Isotretinoin--13-cis-Retinoic acid used in the systemic therapy is the most potent drug--treating acne which has not reacted to any conventional methods of therapy.
寻常痤疮是青春期最常见的皮肤病，因其发病部位特殊，病程往往较长，而且在某些患者中，会留下瘢痕形式的畸形，从而可能导致心理社会领域的障碍。用于痤疮局部和全身治疗的药物应具备以下特性：抗皮脂溢、杀菌、抑菌、消炎、抗粉刺炎症、抗粉刺形成。在寻常痤疮的局部和全身治疗中，都会使用四环素、红霉素和克林霉素等抗生素。用于痤疮局部治疗的其他药物有壬二酸、过氧化苯甲酰、维甲酸（维甲酸和13-顺式维甲酸——异维甲酸）。用于全身治疗的异维甲酸——13-顺式维甲酸是治疗痤疮最有效的药物，适用于对任何传统治疗方法均无反应的痤疮。
