De Clercq D, Vercruysse J, Picquet M, Shaw D J, Diop M, Ly A, Gryseels B
Région Médicale de Saint Louis, Programme ESPOIR, Saint Louis, Senegal.
Trop Med Int Health. 1999 Aug;4(8):544-50. doi: 10.1046/j.1365-3156.1999.00444.x.
A village with mixed Schistosoma mansoni and S. haematobium infections (probably in a early endemic phase) was identified around the Lac de Guiers in the Senegal River Basin. In documenting the epidemiology of both schistosomes, we focused on prevalence and intensity of infection, transmission patterns and the impact of treatment. S. mansoni prevalences (near 100%) and egg counts (overall geometric mean eggs per gram of faeces (epg) of 589 were high in all age groups, with 35% of individuals excreting > 1000 epg, and showing a slow decline in egg output only after the age of 30 years. The overall prevalence (28%) and egg counts (2% > 50 eggs/10 ml) of S. haematobium were low, with mean counts of 6.3 eggs/10 ml. Maximal mean S. mansoni egg counts were found in 5-9 year-old boys and in 15-19 year-old girls; S. haematobium maximal counts in 1-4 year-old boys and in girls aged 5-9. Extremely high Biomphalaria pfeifferi infection ratios were recorded over the whole year. Following a single treatment, re-infection was rapid with prevalences and mean egg counts of both Schistosoma species reaching pretreatment levels within 7 months.
在塞内加尔河流域的吉尔湖周边发现了一个同时感染曼氏血吸虫和埃及血吸虫的村庄（可能处于早期流行阶段）。在记录这两种血吸虫的流行病学情况时，我们重点关注感染率、感染强度、传播模式以及治疗效果。曼氏血吸虫的感染率（接近100%）和虫卵计数（每克粪便虫卵几何平均数总体为589个）在所有年龄组中都很高，35%的个体每克粪便虫卵排泄量超过1000个，且仅在30岁以后虫卵排出量才缓慢下降。埃及血吸虫的总体感染率（28%）和虫卵计数（2%超过50个虫卵/10毫升）较低，平均计数为6.3个虫卵/10毫升。曼氏血吸虫虫卵计数最高值出现在5 - 9岁男孩和15 - 19岁女孩中；埃及血吸虫虫卵计数最高值出现在1 - 4岁男孩和5 - 9岁女孩中。全年记录到极高的费氏扁卷螺感染率。单次治疗后，再感染迅速，两种血吸虫的感染率和平均虫卵计数在7个月内就达到了治疗前水平。
