Thonnon J, Picquet M, Thiongane Y, Lo M, Sylla R, Vercruysse J
Unit of Arbovirology, Institut Pasteur de Dakar, Senegal.
Trop Med Int Health. 1999 Aug;4(8):580-5. doi: 10.1046/j.1365-3156.1999.00437.x.
After the Rift valley fever (RVF) epidemic of 1987 in the Senegal River Basin, RVF surveillance based on serosurveys has been conducted for 10 years. Serum samples were obtained from 1336 persons and from sheep and goats in selected areas, and these were tested for IgG/IgM RVF antibodies by ELISA. After a period of regular decrease in RVF prevalence in domestic animals until 1993, an epizootic was observed in all herds in 1994-95 with increases in IgM levels and abortions. During the same period, no human cases or RVF IgM were detected. The RVF IgG prevalence significantly correlated with date of birth: children born after 1987 have a low prevalence (5%) in clear contrast to the older population (25.3%) in Podor district. A retrospective analysis of rainfall and RVF prevalence in small domestic animals over the last 10 years showed that the re-emergence correlated with heavy rainfall. A general analysis of the risk of re-emergence and the efficiency of this RVF surveillance system are presented.
1987年塞内加尔河流域发生裂谷热（RVF）疫情后，基于血清学调查的RVF监测已开展了10年。从选定地区的1336人以及绵羊和山羊身上采集了血清样本，并通过酶联免疫吸附测定法（ELISA）检测了这些样本中的RVF IgG/IgM抗体。在家畜中，RVF流行率在1993年之前呈定期下降趋势，之后在1994 - 1995年期间，所有畜群均出现了 epizootic，IgM水平升高且出现流产情况。同一时期，未检测到人类病例或RVF IgM。RVF IgG流行率与出生日期显著相关：1987年以后出生的儿童流行率较低（5%），这与波多尔地区年龄较大人群（25.3%）形成鲜明对比。对过去10年小型家畜的降雨情况和RVF流行率进行回顾性分析表明，疫情再次出现与暴雨有关。本文对疫情再次出现的风险以及该RVF监测系统的效率进行了综合分析。 （注：epizootic这个词在医学专业文献中可能有特定含义，这里保留英文未翻译，需结合专业知识进一步理解其准确意思）
