Redmond G P
Center for Health Studies, Cleveland, Ohio 44122, USA.
Int J Fertil Womens Med. 1999 Jun-Aug;44(4):193-7.
Female sexual function, as well as sexual dysfunction often seen during menopause, is assumed to be closedly related to the hormonal milieu of the body, particularly that of the target organs of the sex steroids. Estrogen as the hormone associated with female reproductive functioning is given first consideration in treating complaints of dysfunction, especially dyspareunia. However, simply restoring some, or all, of the estrogenization of the premenopausal years does not always lead to improvement in overall sexual functioning. Decreased libido is often still present in situations that appear to be anatomically satisfactory. Thus, exogenous testosterone, in a number of dosage forms, is often used adjunctively. Although the results are often gratifying, side effects may be a problem for some women. Treated women should be monitored for increased facial oiliness, acne, hirsutism, and alopecia.
女性性功能以及更年期常见的性功能障碍，被认为与身体的激素环境密切相关，尤其是与性类固醇靶器官的激素环境相关。雌激素作为与女性生殖功能相关的激素，在治疗性功能障碍，尤其是性交困难的主诉时首先会被考虑。然而，仅仅恢复绝经前几年的部分或全部雌激素水平，并不总是能改善整体性功能。在解剖结构看似正常的情况下，性欲减退往往仍然存在。因此，多种剂型的外源性睾酮常被用作辅助治疗。尽管结果往往令人满意，但副作用可能对一些女性来说是个问题。接受治疗的女性应监测面部油脂分泌增加、痤疮、多毛症和脱发等情况。
