Stewart D, Simpson G T, Nader N D
Department of Anesthesiology, State University of New York at Buffalo, USA.
Reg Anesth Pain Med. 1999 Sep-Oct;24(5):467-9. doi: 10.1016/s1098-7339(99)90016-0.
Anisocoria after sinus surgery can be related to serious complications such as intraorbital hematoma or increased intracranial pressure secondary to an expanding hematoma.
A 51-year-old man underwent endoscopic surgery of sinuses, and developed anisocoria; likely a result of the local spread of cocaine used to provide local anesthesia and vasoconstriction. The localized effect of this anesthetic agent produced a typical picture of nasociliary ganglion block that subsided in a few hours. In the results, the nasociliary nerve block was noticed on recovery from anesthesia with no other neurologic deficit. Ophthalmologic examination demonstrated a short-lasting anisocoria with loss of accommodation and sensory block over the tip of the nose.
The central spread of the local anesthetics should be considered as a differential diagnosis of unexplained anisocoria, especially when it is associated with loss of corneal reflex.
鼻窦手术后出现的瞳孔不等大可能与严重并发症有关,如眶内血肿或因血肿扩大继发的颅内压升高。
一名51岁男性接受了鼻窦内镜手术,并出现了瞳孔不等大;这可能是用于局部麻醉和血管收缩的可卡因局部扩散所致。这种麻醉剂的局部作用产生了典型的鼻睫神经节阻滞表现,数小时后消退。结果显示,麻醉恢复时发现鼻睫神经阻滞,无其他神经功能缺损。眼科检查显示存在短暂的瞳孔不等大,伴有调节功能丧失和鼻尖感觉阻滞。
局部麻醉药的中枢扩散应被视为不明原因瞳孔不等大的鉴别诊断,尤其是当它与角膜反射消失相关时。