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腰骶部脂肪瘤手术后的结果:早期和晚期病情恶化的意义

Results after surgery for lumbosacral lipoma: the significance of early and late worsening.

作者信息

Van Calenbergh F, Vanvolsem S, Verpoorten C, Lagae L, Casaer P, Plets C

机构信息

Department of Neurosurgery, University Hospital Gasthuisberg, Catholic University, Herestraat 49, B-3000 Leuven, Belgium,

出版信息

Childs Nerv Syst. 1999 Sep;15(9):439-42; discussion 443. doi: 10.1007/s003810050433.

Abstract

We retrospectively reviewed 32 patients operated on for lipoma of the conus and lipomyeloschisis, the two main anatomical subtypes of congenital lumbosacral lipomas associated with tethered cord syndrome. Surgery was proposed to patients when they were symptomatic, and in most cases for progressive symptoms. The evolution of the different symptoms was studied separately. In most patients, symptoms improved or stabilized after surgery; in some, however, postoperative worsening, at least of some of the symptoms, was seen. This postoperative worsening became apparent either early or late after the operation, and was not associated with surgical trauma or postoperative complications. We suggest it was caused mainly by the natural course of the disease (especially in the case of the orthopedic deformities), and in some cases by retethering. Our series is not large enough to detect statistical significance for the different symptoms or for the anatomical subgroups. Importantly, according to our analysis by the different symptoms, the operation did not seem to protect the patients from later development of new deficits. This can be interpreted as an argument against prophylactic surgery in asymptomatic patients.

摘要

我们回顾性研究了32例因圆锥脂肪瘤和脂肪脊髓脊膜膨出而接受手术的患者,这是与脊髓拴系综合征相关的先天性腰骶部脂肪瘤的两种主要解剖亚型。当患者出现症状时,大多数情况下是由于症状进展而建议进行手术。对不同症状的演变进行了单独研究。大多数患者术后症状改善或稳定;然而,在一些患者中,至少部分症状出现了术后恶化。这种术后恶化在术后早期或晚期出现,与手术创伤或术后并发症无关。我们认为这主要是由疾病的自然病程(特别是在骨科畸形的情况下)引起的,在某些情况下是由再拴系引起的。我们的系列病例数量不足以检测出不同症状或解剖亚组之间的统计学差异。重要的是,根据我们对不同症状的分析,手术似乎并不能保护患者避免后期出现新的功能障碍。这可以被解释为反对对无症状患者进行预防性手术的一个论据。

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