抗生素预防在急性胰腺炎治疗中的作用。

The role of antibiotic prophylaxis in the treatment of acute pancreatitis.

作者信息

Ratschko M, Fenner T, Lankisch P G

机构信息

Central Pharmacy, Municipal Clinic of Lüneburg, Germany.

出版信息

Gastroenterol Clin North Am. 1999 Sep;28(3):641-59, ix-x. doi: 10.1016/s0889-8553(05)70078-9.

DOI:10.1016/s0889-8553(05)70078-9

PMID:10503141

Abstract

Infected necrosis in acute pancreatitis is one of the most dreaded complications of acute pancreatitis. Whereas selection of an appropriate antibiotic treatment of the infection poses no problem, prophylactic application of antibiotic remains controversial in the absence of symptoms of infection, but where contrast-enhanced CT scan clearly proves necrosis. This article discusses the present state of the art of the role of antibiotic prophylaxis in the treatment of acute pancreatitis and provides clinical guidelines.

摘要

急性胰腺炎中的感染性坏死是急性胰腺炎最可怕的并发症之一。虽然选择合适的抗生素治疗感染不存在问题，但在没有感染症状但增强CT扫描明确证实有坏死的情况下，抗生素的预防性应用仍存在争议。本文讨论了抗生素预防性应用在急性胰腺炎治疗中的现状，并提供了临床指南。